hrp0092lb-18 | Late Breaking Posters | ESPE2019

Exploratory Case-Control Study on ACE2 Expression in Children with Short Stature

Tornese Gianluca , Tonon Federica , Nicolardi Francesca , Chiara Pellegrin Maria , Toffoli Barbara , Faleschini Elena , Barbi Egidio , Fabris Bruno , Bernardi Stella

Background: Short stature is one of the most common presentations to paediatric endocrinologists. It is estimated that despite all the exams, in 50–90% of cases, children are labeled as having idiopathic short stature. It has been recently reported that genetic ACE2 deficiency is associated with reduced body weight as well as with impaired gestational weight gain and fetal growth restriction in pregnancy. It has been argued that ACE2 deficiency, which...